The last letter game is too easy. Let’s up the ante and make a last TWO letters game. It’s possible to lose this game: if you write a word whose last two letters cannot be used to start another English word. Example: someone writes “orgy” and you follow up with “gym”, you lose because there’s no English word that begins with the letters “ym”.
You can find a word anyway you want (own knowledge, looking it up, phone a friend). The only rule is that it must have an entry in either
http://www.dictionary.com/ or
https://www.merriam-webster.com/. But in the interest of keeping things fun, please don't rely on outside sources too much
I’ll begin with an easy one:
Carcinoma
