SHIFT + Mouse Button 4 & 5

Hi all, had some issues with a game and overall configuration and thought to ask here. I am playing AgeOfEmpires2DE and tried to map a hotkey to my Razer Deathadder Elite and it didnt work. The button i tried was the side buttons, 4 and 5. The game actually registers them as "Extra Mouse Button 4 and 5" but they dont work with the SHIFT key.

They do work alone by themselves, just not with SHIFT or Ctrl.

So if i use any other button like the scroll wheel with the SHIFT key it works but just not the side buttons. For example SHIFT+ Scroll Up works fine, Ctrl + Scroll Up also works great but neither of the Side Buttons 4 &5 work with SHIFT or Ctrl.

Not sure if this is a game issue or Windows 10 not allowing my to pair them with the SHIFT and Ctrl.

Any tips?

Also last small concern, can the razer synapse auto change profile linked to seperate games automatically?

Thanks