Naga Pro side scrolling buttons not working with Synapse on | Razer Insider
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So, after I finally managed to solve the Tartarus V2 joystick drifting problem for good, I reinstalled Synapse and plugged back my Naga Pro, and after restoring back my settings and bindings, I now find myself unable to use the left/right scrolling bindings, regardless of the application/game, or the key/binding applied.

If I quit Synapse, the bindings (with profiles saved onboard) works again.

Basically the same as this old thread:

/naga-mouse-scroll-wheel-left-right-stopped-working.32604/

It mentions calibration, but it's a feature I never used.
Did you already try to repair the Synapse application? If not yet, just follow the steps here. If you're still experiencing the same issue, please let me know through PM so I can start a case to raise your concern to the Software Team.