Naga Trinity dont register clicks.

I have problem with Naga Trinity. In games or while browsing it periodicaly stops to register right or left (maybe other buttons) clicks of mouse. It happes in ~ 2 minute and lasts 2-3 seconds, while mouse cursor moves, clicks just dont work for several moments. I tried every possible method I found in internet, turned energy saving for usb and devices off, reinstalled synapse with not working antivirus, got all updates on windows. Hardware part seem ok, because if synapse 3.0 uninstalled and default microsoft driver used mouse works perfectly, no click skipping, but of corse cant change mouse profiles without synapse. Also mouse dont shows in synapse 3.0 after reboot , until plugged out and put back.

My system is Windows 10 pro 1909 fully updated.