I did some digging, and I’m having that same issue. What’s causing it is the recent update. So, we’re gonna have to wait until they come out with a newer update that fixes this problem for Razer Synapse.

+1 guys, i’ve the same issue since the last update ! Uninstalling and fresh installs don’t help .. . 

same problem for me :|  @Razer Admin fix this pls 

same problem for me :|  @Razer Admin fix this pls 

See my comment, That is the solution

This is ridiculous. I’ve tried everything on their razer support. I’ve watched every single video, deleted temp files, clean install, I mean everything. My PC case, mouse, Keyboard and the Tartarus keyboard are all Razer.

This works for me too ! thx man !

Trying now, Cheers

I

This works!!! Thanks!!!

I installed the old version and it actually opened but it does not recognize my razer headphones

So do I with my razer mice

The only thing working for me consistently is as follows:

1. ISSUE - Razer synapse not recognizing my tartarus gamepad profile on startup; Synapse software not launching
2. FIX - In Task Manager, End process on ALL Razer Synapse or related processes (including Chroma profiles for lighting etc.). 
   1. Run as Admin, Synapse launches

Def seems tied to recent update, so we’ll have to wait :-(