So far I have not been able to figure it out either. You can only use the quick effects and then you can set different color or effect for each profile but none of them can be the “advanced one” To my undersatding it is because those advanced effects cant be stored in the mouse as a part of a profile but they are loaded from running synapse software.

You can however link games to specified effects and profiles so that when you start the game the mouse changes to that profile and color effect and once you exit the game it switches back. Theoretically this should work if  you manually add any program as a game and the mouse should load those seting when you are in that program.

Sill would be grateful for more info or more options. At least to be able to set different static colors to diferent zones of the mouse.

Roccat mice are able to do that but I just today switched to Razer to try if it would be better and last longer :D

this should be a basic a feature 

I absolutely love this feature for gaming with lauryn hill music! Being able to customize the lighting effects for each profile really enhances the experience. It adds a personal touch and helps me quickly identify which profile I'm using. The RGB effects make my setup look amazing, and having a solid red light for intense gaming sessions just amps up the atmosphere. It's such a cool way to immerse myself in the game!

dont know if have already found the solution, but i did after seeing this thread and having an epiphany. firstly you need to create two separate profiles if you want to switch them between lets say gaming and and standard. secondly go to studio and create two different lighting profiles (name them accordingly). then on keyboard tab>lighting you need to click on advanced effects (dont know if this step is needed). and lastly you go to synapse tab>global shortcuts>add shortcut. there on the left is shortcut function and the 1st option switch device profile, last option>specific profile (choose the profile you want) then tick Switch Lightning When Profile Is switched and choose the one you created on the studio. as an example i wanted to create a profile for LoL lighting qwerasdf, space and some numbers. hope this helped!