Global Shortcuts not working with Synapse 3

Hi , I have a support question about the Global Shortcuts , and I have tried to find the solution in previous threads where I see several other seems to have similar issues . The issue for me is that I have made a few "Global Shortcuts" to allow me to change the PROFILE between the ones for GAMES , WORK and SCHOOL , this worked prior with my old Synapse 2 which was disabled and removed after Synapse 3 was installed with my new mouse . unfortunately both my macros and old Global shortcuts was gone , but I restored most of the macros and created new Global Shortcuts , but the global shortcuts does not seem to be working no matter what I do !. Any tips ? Kind Regards André