Is there a way to disable/enable macros with a keybind?

Imagine this. When I press a keybind, it enables / disables a macro. I have a macro that clicks automatically for me wheh I press down left button or hold it. And when i press that keybind, it activates the macro and when i press left mouse button it clicks for me. But when i press the keybind again, disabling it, the macro doesnt work and the left click functions normally. Is there any way i can set a keybind to disable a macro?