Similar problem as this thread :

I’m on Windows 10, and single keybinds save to profiles just fine. I’m using firmware version 1.1.0.0 and version 3.8.731.72514 of Synapse updated just a few days ago on 8/18/23. It only has to be as complex as “Ctl+PgUp” or “Alt+Left_Arrow” for this to not save. I’m not doing super long macros. Just little things for navigating in a browser. It works fine if Synapse is open, but immediately stops working as soon as the app is closed. I could understand this being the case for the cheaper Hyperspeed, but the Naga V2 Pro is supposed to come with these features working. The weird thing is this ONLY affects the macros, and nothing else. I’ve seen similar threads open for over 2 years now, with it sometimes working and sometimes not for various users. I’m dreading how long this will take to fix. My initial Amazon review was moderately praiseworthy, but I may have to alter it if this doesn’t get fixed within the next month or so. I understand reloading profiles into Synapse is a workaround, but this shouldn’t have to be done, especially after 2 years. It’s a shame because the hardware is genuinely nicer than the competition, but the firmware is just amateurish at best.