Synapse 3 Macro - F4 (Win Shortcut) and Alt + F4 (Win Default)

Hello - New to Razer and have just purchased a Blackwidow V3 using Synapse 3. I have created a macro for F4 to run the Windows Calculator. But when trying to use the default Alt + F4 to close an app, it runs the Windows Calculator app. How can I set it up so that Alt + F4 doesn't trigger the F4 key as a separate key? Is there a way to use the F4 key (or any function key) in a number of combinations? Also, when trying to record Alt + F4 the bigger issue is that it closes the Synapse App and I lose access to all my Macros for a bit (I'm guessing that it is still recording even though Windows closed the app and I am not able to stop recording or save the macro). Maybe they never thought about this particular key combination but I am hoping that I am missing something and that it is easy to record this combination and use it in addition to the standard F4 key. Thanks for any help that you can provide.