Start/stop peripheral macro without sending call to win32api via script?

Hi, i'd like to know if i can toggle on/off the macros crated by synapse via some kind of script language (maybe python), so i can send the message to the synapse driver and not directly to windows (normally using pyautogui or any other automation macro). The application i'm automating blocks these win32api calls, but the synapse macro is accepted. after i use the win32api calls, the default action is send or in most cases they are blocked. can i communicate to the synapse like i was the mouse itself (mimic) and call the macro correctly? any ideas?