Cortex possible interference/conflict with OC-software or BIOS settings?

Hi there, I'm a bit curios when it comes to Cortex and the game/system booster/optimization and "compatibility" with BIOS OC or MSI Afterburner for example. Let's say you have an 8-core CPU and are playing Counter strike, won't enabling all 8 cores at full speed decrease the max speed for the cores that are actually utilized for the game? And the option "change power settings to high performance", is it the windows power plan they're referring to? Can anyone think of any reason of possible conflict issues between Cortex booster and overclocking settings?